Drug Design

Module Code
BI5002
Module Coordinators
Andreas Peter Dominik
Teachers
Andreas Peter Dominik
Short Description
General techniques of computer-assisted drug design are introduced and applied to real-life examples.
Learning Objectives

Students are familiar with the techniques of today's drug design. They know general algorithms and are capable to apply them to questions of computer-assisted drug design. They can hold their own in interdisciplinary teams in the field of pharmaceutical re-search and discuss with colleagues of other disciplines.

Contents
  • Structure of biomolecules and drugs
  • Simulation of biomolecules and drugs
  • Computer-assisted design of chemical molecules and biomolecules
  • Application of public domain tools and implementation of own software tools
Duration in Semester
1
Instruction Language
German
Total Effort
6 CrP; an estimated 180 hours, of which approximately 60 are spent in class.
Weekly School Hours
4
Method of Instruction
Lecture 2 sppw Practical Course 2 sppw
Requirements for the awarding of Credit Points
Written exam
Evaluation Standard
according to examination regulations (§ 9)
Availability
Yearly
References
  • G. Klebe: Wirkstoffdesign Spektrum Akademischer Verlag
  • T. Lengauer (Editor): Bioinformatics – From Genomes to Drugs, Vol. 1 und 2 Wiley-VCH
  • A.R. Leach, V.J. Gillet: An Introduction to Chemoinformatics Springer-Verlag
Prerequisites
Fundamental knowledge on chemistry, biochemistry, physics and bioinformatics.