Current research projects

Development of downstream processes for nanoplexes

  • Development of vaccine formulations


Fig.1: Process overview for the production of Orf virus in mammalian cells1

Projects funded by:

  • Federal Minister for Economic Affairs and Energy (BMWi)
    • Hessian Ministry for Science and the Arts (HMWK)
    • Industry Partners

Development of formulations of biological insecticides

  • Production of viral insecticides in insect cell cultures to control Drosophila suzukii.

Projects funded by:

    • Hessian Ministry for Science and the Arts (HMWK)
    • Federal Ministry of Food and Agriculture (BMEL)

Microfluidic approach for the quantification of infectious virus particles

  • Quantification of a cell culture derived baculovirus (model virus) as well as pharmaceutically relevant viral candidates


Fig.2: Analytical methods for the quantification of viruses and virus-like particles.

Project funded by:

Development of a platform technology for the production of recombinant antimicrobial proteins and peptides


1 K. Lothert, F. Pagallies, F. Eilts, A. Sivanesapillai, M. Hardt, A. Moebus, T. Feger, R. Amann, M.W. Wolff, A scalable downstream process for the purification of the cell culture-derived Orf virus for human or veterinary applications, J. Biotechnol., 323 (2020) 221-230.